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CRISPR-based genome editing has been widely implemented in various cell types. In-silico single g...

關鍵詞: CRISPR    genome editing    in-silico sgRNA design    off-target   
期刊:Sheng Wu Gong Cheng Xue Bao  影響因子:0.0  發表日期: 20171025  PMID: 29082722 


The Cancer Stem Cell (CSC) hypothesis postulates the existence of a small population of cancer ce...

期刊:Methods Mol Biol  影響因子:0.0  發表日期: 20180101  PMID: 28986882 


Today, the CRISPR (clustered regularly interspaced short palindromic repeats) region within bacte...

關鍵詞: CRISPR    Estimation    Evolutionary model    Gain rate    Loss rate   
期刊:Theor Popul Biol  影響因子:1.613  發表日期: 20171122  PMID: 29174635 


CRISPR/Cas9-based gene targeting allows deletion of a gene of interest from cultured cell lines. ...

關鍵詞: CRISPR    CRISPR validation    Immortalized BMDM    Lentivirus    Myeloid    THP-1   
期刊:Methods Mol Biol  影響因子:0.0  發表日期: 20180101  PMID: 29177854 


Genome modification at specific loci in livestock species was only achievable by performing homol...

關鍵詞: CRISPR    bovine    farm    livestock    pig    transgenic   
期刊:Reprod Domest Anim  影響因子:1.4  發表日期: 20171001  PMID: 29052327 


Viral sequence integration into the mammalian genome has long been perceived as a health risk. In...

關鍵詞: CRISPR    hypothesis    viral sequence integration   
期刊:Viral Immunol  影響因子:1.432  發表日期: 20171101  PMID: 29028182 


Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) system is a novel type of inn...

期刊:J Basic Microbiol  影響因子:0.0  發表日期: 20160601  PMID: 26871258 


The eastern North American monarch butterfly, Danaus plexippus, is an emerging model system to st...

期刊:G3 (Bethesda)  影響因子:0.0  發表日期: 20160407  PMID: 26837953 


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