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In this issue of Cancer Cell, Ishizawa et?al. describe the hyperactivation of ClpP as a strategy ...

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期刊:Cancer Cell  影響因子:23.916  發表日期: 20190513  PMID: 31085171 


In this issue of Cancer Cell, Elgendy et?al. describe the use of intermittent fasting as a strate...

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期刊:Cancer Cell  影響因子:23.916  發表日期: 20190513  PMID: 31085172 


During the development and progression of tumors, cancer cells undergo clonal selection due to a ...

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期刊:Cancer Cell  影響因子:23.916  發表日期: 20190513  PMID: 31085173 


Inflammatory cells are important for tumor initiation and promotion, providing cancer cells with ...

期刊:Cancer Cell  影響因子:23.916  發表日期: 20190513  PMID: 31085174 


Ripretinib (DCC-2618) was designed to inhibit the full spectrum of mutant KIT and PDGFRA kinases ...

關鍵詞: GIST    KIT    PDGFRA    conformational switch control    imatinib    mastocytosis    regorafenib    resistance    ripretinib    sunitinib   
期刊:Cancer Cell  影響因子:23.916  發表日期: 20190513  PMID: 31085175 


Drug-tolerant "persister" tumor cells underlie emergence of drug-resistant clones and contribute ...

期刊:Cancer Cell  影響因子:23.916  發表日期: 20190513  PMID: 31085176 


Although immune checkpoint blockers have yielded significant clinical benefits in patients with d...

期刊:Cancer Cell  影響因子:23.916  發表日期: 20190513  PMID: 31085177 


High-grade gliomas defined by histone 3 K27M driver mutations exhibit global loss of H3K27 trimet...

期刊:Cancer Cell  影響因子:23.916  發表日期: 20190513  PMID: 31085178 


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