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In this issue of Cancer Cell, Jiang et?al. report a genomic and transcriptional analysis of tripl...

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期刊:Cancer Cell  影響因子:23.916  發表日期: 20190318  PMID: 30889376 


Tumors resistant to PARP inhibitors frequently show signs of replication stress, with hyper-activ...

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期刊:Cancer Cell  影響因子:23.916  發表日期: 20190318  PMID: 30889377 


Activating mutations in GNAQ/GNA11, encoding Gαq G proteins, are initiating oncogenic events in u...

關鍵詞: FAK    G protein    GNA11    GNAQ    Hippo    MOB1    PTK2    YAP    signal transduction    uveal melanoma   
期刊:Cancer Cell  影響因子:23.916  發表日期: 20190318  PMID: 30773340 


RNA-binding proteins (RBPs) are essential modulators of transcription and translation frequently ...

關鍵詞: AML    CRISPR    DCAF15    RBM39    RNA-binding proteins    alternative splicing    leukemia    spliceosome    sulfonamides   
期刊:Cancer Cell  影響因子:23.916  發表日期: 20190318  PMID: 30799057 


Increasingly effective therapies targeting the androgen receptor have paradoxically promoted the ...

期刊:Cancer Cell  影響因子:23.916  發表日期: 20190318  PMID: 30827887 


Ionizing radiation (IR) and chemotherapy are standard-of-care treatments for glioblastoma (GBM) p...

關鍵詞: DNA damage    FGFR2    GBM    PTEN    ionizing radiation (IR)    tyrosine phosphorylation   
期刊:Cancer Cell  影響因子:23.916  發表日期: 20190318  PMID: 30827889 


We comprehensively analyzed clinical, genomic, and transcriptomic data of a cohort of 465 primary...

期刊:Cancer Cell  影響因子:23.916  發表日期: 20190318  PMID: 30853353 


A report in this issue of Cancer Cell identifies the RNA-binding protein RBM39 as a potential tar...

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期刊:Cancer Cell  影響因子:23.916  發表日期: 20190318  PMID: 30889374 


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