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Driver mutations in oncogenes encode proteins with gain-of-function properties that enhance fitne...

關鍵詞: cancer    competitive fitness    exaptation    oncogenes    selection    targeted therapy   
期刊:Cancer Cell  影響因子:23.916  發表日期: 20181112  PMID: 30393068 


Tumor-reactive T?cell exhaustion prevents the success of immune therapies. Pegilodecakin activate...

期刊:Cancer Cell  影響因子:23.916  發表日期: 20181112  PMID: 30423297 


In this issue of Cancer Cell, Volk et?al. report that overexpression of CHAF1B displaces myeloid ...

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期刊:Cancer Cell  影響因子:23.916  發表日期: 20181112  PMID: 30423290 


The fate of disseminated tumor cells is largely determined by microenvironment (ME) niche. The os...

期刊:Cancer Cell  影響因子:23.916  發表日期: 20181112  PMID: 30423299 


Deregulated HER2 is a target of many approved cancer drugs. We analyzed 111,176 patient tumors an...

期刊:Cancer Cell  影響因子:23.916  發表日期: 20181112  PMID: 30449325 


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期刊:Cancer Cell  影響因子:23.916  發表日期: 20181112  PMID: 30423300 


In this study we interrogated the metabolome of human acute myeloid leukemia (AML) stem cells to ...

期刊:Cancer Cell  影響因子:23.916  發表日期: 20181112  PMID: 30423294 


Histopathological diagnosis of biopsy samples and margin assessment of surgical specimens are cha...

期刊:Cancer Cell  影響因子:23.916  發表日期: 20181112  PMID: 30344004 


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